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Getting New Pain Drugs to Market: 3 Challenges
Each September, pain advocates and specialists raise awareness about issues facing the millions of people living with chronic pain. One of the most pressing? The lack of treatments available to alleviate suffering.…
Where Does Placebo Response in Clinical Trials Come From? 6 Influences
Placebo response is a major source of noise in trial data analysis, muddying the results and making it more difficult to detect true treatment effect. We know…
Clinical Trial Statistical Analysis: How to Minimize Noise
The main objective of most clinical trials is to evaluate efficacy and safety of an experimental treatment. To do this, statisticians compare the response of the drug-treated…
How to Increase Clinical Study Power with Covariate Adjustment
Adjustment for covariates helps clinical trial statisticians demonstrate differences in drug effect between groups of people. In this blog, we discuss what this means and how it…
Patient Psychology: The Missing Link in Understanding Clinical Trial Data
Patients are central to clinical trials – but the impact of patient psychology on clinical trial results is still poorly understated. In this blog, we discuss why…
Placebo Effect vs. Placebo Response: Is There A Difference?
Placebo effect and placebo response are often used interchangeably – despite being two different phenomena. In this blog, we highlight the differences—and why it matters. Placebos are an important…
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