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Education

Getting New Pain Drugs to Market: 3 Challenges

Each September, pain advocates and specialists raise awareness about issues facing the millions of people living with chronic pain. One of the most pressing? The lack of treatments available to alleviate suffering.…

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Education

Where Does Placebo Response in Clinical Trials Come From? 6 Influences

Placebo response is a major source of noise in trial data analysis, muddying the results and making it more difficult to detect true treatment effect. We know…

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Education

Clinical Trial Statistical Analysis: How to Minimize Noise

The main objective of most clinical trials is to evaluate efficacy and safety of an experimental treatment. To do this, statisticians compare the response of the drug-treated…

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Education

How to Increase Clinical Study Power with Covariate Adjustment

Adjustment for covariates helps clinical trial statisticians demonstrate differences in drug effect between groups of people. In this blog, we discuss what this means and how it…

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Education

Patient Psychology: The Missing Link in Understanding Clinical Trial Data

Patients are central to clinical trials – but the impact of patient psychology on clinical trial results is still poorly understated. In this blog, we discuss why…

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Education

Placebo Effect vs. Placebo Response: Is There A Difference?

Placebo effect and placebo response are often used interchangeably – despite being two different phenomena. In this blog, we highlight the differences—and why it matters.   Placebos are an important…

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