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How to Increase Clinical Study Power with Covariate Adjustment
Adjustment for covariates helps clinical trial statisticians demonstrate differences in drug effect between groups of people. In this blog, we discuss what this means and how it…
Patient Psychology: The Missing Link in Understanding Clinical Trial Data
Patients are central to clinical trials – but the impact of patient psychology on clinical trial results is still poorly understated. In this blog, we discuss why…
Placebo Effect vs. Placebo Response: Is There A Difference?
Placebo effect and placebo response are often used interchangeably – despite being two different phenomena. In this blog, we highlight the differences—and why it matters. Placebos are an important…
Mitigating the Placebo Response in Phase II & III Clinical Trials
Phase II and III trial failure due to unexpectedly large placebo response rates is still all too common. In this blog, we explain what this means and…
Understanding the Placebo Effect: Increasing Clinical Trial Success
Placebos are used in randomized, placebo-controlled controlled trials, in which one group (or more) receives the active treatment and the other group receives the placebo control. This…
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