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The Placebo response in drug development Part 5: Pain
Placebo-controlled clinical trials are the gold standard in drug development, in part to ensure that the efficacy of a new therapy exceeds the placebo response in the…
Accounting for the high reduction of power due to floor effect in design of randomised controlled trials
Abstract Purpose Outcomes in Randomized Controlled Trials (RCT) are often computed as changes from baseline of finite scales…
The Placebo response in drug development Part 5: Pain
Placebo-controlled clinical trials are the gold standard in drug development, in part to ensure that the efficacy of a new therapy exceeds the placebo response in the…
Clinical Trial Technology: Why IT Infrastructure & Security Matters
From internal communication and management systems to tools sponsors deploy to improve operations and results, technology is everywhere in the clinical trial landscape. However, these technologies are…
Clinical Trial Technology & Project Management:
4 Aspects of Cognivia’s Approach
Many sponsors err on the side of reluctance when incorporating new technology in clinical trials. This is because some technologies have the potential to overly burden not…
Q&A: Experts’ Perspectives on the Placebo Response in Clinical Trials
Experts shared their perspectives from real-world trials on both classical and new approaches to manage the placebo response – and some questions arose throughout the discussion.
The Power of Placebo & Trust for Pain Management
A growing body of work has demonstrated that pain perception can be modulated by social, cultural, contextual and interpersonal factors.1,2,3,4 Beyond this, patient trust in their doctor –…
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