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Leveraging historical data to optimize the number of covariates and their explained variance in the analysis of randomized clinical trials
The amount of data collected from patients involved in clinical trials is continuously growing. All baseline patient characteristics…
Impact of excluding highly variable pain subjects on the treatment estimation
The baseline pain variability (BPV) has often been presented as positively correlating with the placebo response (PR) and…
Leveraging historical data for covariate adjustment in the analysis of randomized clinical trials
Scientific Poster presented on October 2021 at the Annual Meeting of the Royal Statistical Society of Belgium. The amount…
Should placebo responders be excluded from RCTs?
Scientific Poster presented on September 2021 at the International Society for CNS Clinical Trial and Methodology Conference The…
Modeling of the Placebo Response in Parkinson’s Disease
The magnitude and the variability of the placebo response have a confounding influence when testing the superiority of active compounds…
Towards an automated rating of the MDS-UPDRS motor scores
Tools4Patient has developed an IMU-based device where sensors are placed on the tip of the index finger and thumb bilaterally. The device was…
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