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Leveraging historical data for high-dimensional regression adjustment, a machine learning approach.
The amount of data collected from patients involved in clinical trials is continuously growing. All those patient’s characteristics…
Baseline Pain Measurements As Predictors Of The Placebo Response In Neuropathic Patients
In analgesia randomized clinical trials (RCTs), the magnitude of the placebo response has a negative influence when testing…
Bayesian Modeling Of The Placebo Response In Neuropathic Pain
In analgesia randomized clinical trials (RCTs), the magnitude and the variability of the placebo response have a negative…
Multifactorial Aspect Of The Placebo Analgesia Response In Peripheral Neuropathic Patients
The placebo response exerts a confusing influence when testing the statistically significant superiority of active compounds compared to…
Characterization And Prediction Of Placebo Responders In Peripheral Neuropathic Patients In A 4-week Analgesic Clinical Trial
In analgesia randomized clinical trials (RCTs), the magnitude of the placebo response tends to increase with the year…
Do Environmental Parameters Influence The Prediction Of The Placebo Response?
This proof-of-concept study on peripheral neuropathic pain patients investigates the potential influence of the investigator on the placebo…
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