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Embracing Human Complexity in Clinical Research
As clinical trials become more diverse, patient heterogeneity, placebo responses, and inter-site variability become more pronounced, contributing to high rates of failed trials and extended development timelines…
The Characterization of Individual Patient Placebo Response: Impact on the Clinical Study Power
Learn about the Placebell©™ method, its development in chronic pain., and how it can be easily implemented to increase study power and de-risk clinical trials.
Video Interview at Partnerships in Clinical Trials, Europe 2017
Dominique Demolle, CEO speaks with Andy Burrows of PCT TV about the early vision and development of Placebell©™ at Partnerships in Clinical Trials, Europe
Baseline Pain Measurements As Predictors Of The Placebo Response In Neuropathic Patients
In analgesia randomized clinical trials (RCTs), the magnitude of the placebo response has a negative influence when testing…
Bayesian Modeling Of The Placebo Response In Neuropathic Pain
In analgesia randomized clinical trials (RCTs), the magnitude and the variability of the placebo response have a negative…
Multifactorial Aspect Of The Placebo Analgesia Response In Peripheral Neuropathic Patients
The placebo response exerts a confusing influence when testing the statistically significant superiority of active compounds compared to…
Characterization And Prediction Of Placebo Responders In Peripheral Neuropathic Patients In A 4-week Analgesic Clinical Trial
In analgesia randomized clinical trials (RCTs), the magnitude of the placebo response tends to increase with the year…
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