May 26, 2021

Adjustment for covariates helps clinical trial statisticians demonstrate differences in drug effect between groups of people. In this blog, we discuss what this means and how it can help improve analysis and interpretation of clinical trial data.

April 29, 2021

Patients are central to clinical trials – but the impact of patient psychology on clinical trial results is still poorly understated. In this blog, we discuss why psychology matters and how to better account for it in trial data.

April 1, 2021

Placebo effect and placebo response are often used interchangeably – despite being two different phenomena. In this blog, we highlight the differences—and why it matters.   Placebos are an important part of clinical research. But the impact of placebo use is a long-discussed matter in the biotech and pharmaceutical industry. While helpful in determining drug efficacy, certain factors make using placebos as drug comparators rather complicated.   Most will say placebo treatment

March 15, 2021

Phase II and III trial failure due to unexpectedly large placebo response rates is still all too common. In this blog, we explain what this means and how clinical trials can better manage the placebo response.

February 9, 2021

Placebos are used in randomized, placebo-controlled controlled trials, in which one group (or more) receives the active treatment and the other group receives the placebo control. This type of study is considered the gold standard of clinical trials for three reasons.