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News

Introducing Cognivia Signal: Early-Warning Behavioral Risk Intelligence for Clinical Trials

Cognivia launches the world’s first early-warning behavioral risk intelligence dashboard—Cognivia Signal—empowering clinical teams to see what’s coming before it happens. Mont-Saint-Guibert, Belgium – October 9, 2025 – Cognivia,…

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Education

How to Increase Clinical Study Power with Covariate Adjustment

Adjustment for covariates helps clinical trial statisticians demonstrate differences in drug effect between groups of people. In this blog, we discuss what this means and how it…

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Webinars

Predicting the placebo response in OA to improve the precision of the treatment effect estimation

The current abstract is the result of a collaboration between Unity biotechnology and Tools4 patient As you know, the placebo response is one of the major sources of variability in randomized clinical trials As a result, many trials fail due to a high placebo response. Unfortunately, this is also true in OA studies. However, within Tools4Patient, we have developed…

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Webinars

Video Presentation – Can Daily Self-Assessment Induce a Learning Effect Mitigating Pain Evaluation Error in Randomized Clinical Trials?

LEARNING EFFECT & EVALUATION ERROR At Tools4Patient, we are working on the prediction of placebo response and especially the placebo response with endpoints assessing the patients’ pain. As you know, these endpoints represent most of the efficacy endpoints in Osteoarthritis Randomized Clinical Trials. Nevertheless, the assessment of…

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Publication

Predicting the Placebo response in OA to Improve the Precision of the Treatment Effect Estimation

Scientific Poster presented on April 2021 at the Osteoarthritis Research Society International Meeting. Purpose In osteoarthritis (OA) randomized…

Type: Scientific Poster
Authors: Samuel Branders1; Jamie Dananberg2; Frederic Clermont1; Ben Xie2; Benjamin Hsu2; J. Visich2; Akbar Khan2; Lauren Masaki2; Alvaro Pereira1 1-Tools4Patient, Mont-Saint-Guibert, Belgium 2-Unity Biotechnology, Inc., South San Francisco, CA
Conference: Osteoarthritis Research Society International (OARSI)
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Publication

Can Daily Self-Assessment Induce A Learning Effect Mitigating Pain Evaluation Error In Randomized Clinical Trials?

Scientific Poster presented on April 2021 at the Osteoarthritis Research Society International Meeting. Purpose Questionnaires assessing  patients’ pain level…

Type: Scientific Poster
Authors: Arthur Ooghe, M.E.; Samuel Branders, Ph.D.; Alvaro Pereira, Ph.D.
Conference: Osteoarthritis Research Society International (OARSI)
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Education

Patient Psychology: The Missing Link in Understanding Clinical Trial Data

Patients are central to clinical trials – but the impact of patient psychology on clinical trial results is still poorly understated. In this blog, we discuss why…

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