Each September, pain advocates and specialists raise awareness about issues facing the millions of people living with chronic pain. One of the most pressing? The lack of treatments available to alleviate suffering. In this blog, we look at three top challenges of getting new pain drugs to market—and offer a potential solution.
A representative from Tools4Patient discusses how grasping the ties between the two can help in reducing the impact of the placebo response in trials.
Placebo response is a major source of noise in trial data analysis, muddying the results and making it more difficult to detect true treatment effect. We know that it’s a pressing problem for clinical trials that needs solving, but where does it come from in the first place? Patient psychology, expectations and baseline severity of the disease play a significant part of a patient’s placebo responsiveness.
When we think about patient characteristics that influence health, disease, and clinical research, we tend to think about things like vital statistics, medical history and genetic makeup – while patient personality or psychology is often overlooked. In reality, the importance of personality has been under scrutiny for centuries and dates back to Greek and Roman times