The baseline pain variability (BPV) has often been presented as positively correlating with the placebo response (PR) and associated with a lack of consistency in the subjects’ pain evaluation. Excluding high BPV subjects should then improve the precision of the treatment response. Another common method to increase the essay sensitivity is to adjust the analysis for covariates
Placebo Response
Placebo response is one of the biggest threats to clinical data analysis– especially when left unchecked. In this blog, we review the top three risks trial scientists must address (and how to address them).
Each September, pain advocates and specialists raise awareness about issues facing the millions of people living with chronic pain. One of the most pressing? The lack of treatments available to alleviate suffering. In this blog, we look at three top challenges of getting new pain drugs to market—and offer a potential solution.
Tools4Patient presented data at the MDS Congress 2021 that predicted the placebo response in Parkinson’s disease (PD) in a multi-center, multi-national clinical study.
Clinical trials measure efficacy of experimental therapies by comparing outcomes in patients receiving therapeutic interventions (treatment response) with patients receiving placebo (placebo response).
A representative from Tools4Patient discusses how grasping the ties between the two can help in reducing the impact of the placebo response in trials.