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News

Introducing Cognivia Signal: Real-Time Behavioral Risk Intelligence for Clinical Trials

Cognivia launches the world’s first real-time behavioral risk intelligence dashboard—Cognivia Signal—empowering clinical teams to see what’s coming before it happens. Mont-Saint-Guibert, Belgium – October 9, 2025 – Cognivia, the AI-driven leader in behavioral science for clinical research, proudly announces the launch of Cognivia Signal, a groundbreaking solution…

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Publication

Analyzing Neuropathic Pain Subjects in Acute Low Back Pain Using an NPSI-Based Stratification Algorithm and PainDETECT Measurement

Background & Aims RCTs in neuropathic pain (NeP) are challenged by the high inter-individual variability in treatment response,…

Type: Scientific Poster
Authors: Alvaro Pereira, Arthur Ooghe, Jérôme Paul, Dmitri Lissin Cognivia, R&D, Mont-Saint-Guibert, Belgium, Scilex Holding Company, R&D, Palo Alto, United States
Conference: Neupsig 2025
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Publication

ARE SITE DIFFERENCES DRIVING OUTCOMES? THE CENTRAL ROLE OF EXPECTATIONS IN OA RCTS.

Purpose Disparities among sites are frequently observed in the results of Randomized Controlled Trials (RCTs).  As a result, adjusting…

Type: Scientific Poster
Authors:
Conference: OARSI 2025
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Publication

From Chronic to Acute Pain: Evaluating the baseline prognostic covariates in Severe Acute Lower Back Pain

The FDA’s 2023 guidance on baseline covariate adjustment highlights the importance of incorporating prognostic covariates into randomized clinical…

Type: Scientific Poster
Authors: Samuel Branders, Arthur Ooghe, Jérôme Paul, Dmitri Lissin, Dominique Demolle, Alvaro Pereira
Conference: United States Association for the Study of Pain 2025
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Publication

Predicting drop-out in early-stage Type 1 Diabetes clinical trials to improve retention through Personalized Engagement Strategies

Background: Patient non-adherence and drop-out increase the time and cost of clinical trials. A tool that predicts, at…

Type: Scientific Poster
Authors: A. Ooghe, J. Van Rampelbergh, S. Branders, N. Xaborov, J. Paul, D. Demolle, A. Pereira
Conference: Advanced Technologies & Treatments for Diabetes 2025
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Publication

Improving Precision of Clinical Trials Results in T1 Diabetes with Transferrable Prognostic Models

Background: In randomized controlled trials (RCTs), assay sensitivity issues can affect both statistical power and the confidence in…

Type: Scientific Poster
Authors: A. Ooghe, J. Van Rampelbergh, S. Branders, N. Xaborov, J. Paul, D. Demolle, A. Pereira
Conference: Advanced Technologies & Treatments for Diabetes 2025
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Insights

Discussion on the Use of Placebell and FDA’s Feedback

Cognivia recently initiated a discussion with the FDA through the “Innovative Science and Technology Approaches for New Drugs (ISTAND) Pilot Program” process. A Letter of Intent (LOI) was…

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