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News

New Cognivia publication on the use of composite covariates to understand complex data in clinical trial data analysis

Covariates are typically used to control for factors that may impact the measurement of outcomes, particularly to describe individual patient characteristics that may or may not relate to treatment response. In fact, all patient baseline characteristics collected are potential covariates linked with the patient’s outcome.

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Publication

Towards an automated rating of the MDS-UPDRS motor scores

Tools4Patient has developed an IMU-based device where sensors are placed on the tip of the index finger and thumb bilaterally. The device was…

Type: Scientific Poster
Authors: Marchal S., Garraux G., Branders S., Bernard G., Billocq C., Pereira A.
Conference: International Parkinson and Movement Disorder Society
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Education

Where Does Placebo Response in Clinical Trials Come From? 6 Influences

Placebo response is a major source of noise in trial data analysis, muddying the results and making it more difficult to detect true treatment effect. We know…

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Insights

The Importance of Patient Psychology in Health and Clinical Research

When we think about patient characteristics that influence health, disease, and clinical research, we tend to think about things like vital statistics, medical history and genetic makeup…

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Education

Clinical Trial Statistical Analysis: How to Minimize Noise

The main objective of most clinical trials is to evaluate efficacy and safety of an experimental treatment. To do this, statisticians compare the response of the drug-treated…

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Insights

The placebo response in drug development. Part 4: Irritable Bowel Disease

As in many other diseases (e.g. pain, osteoarthritis, rheumatoid arthritis, Parkinson’s Disease, etc ), patients participating in clinical trials for IBD treatments may experience a pronounced placebo…

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Multimedia

Predict placebo response using patient psychology to increase trial power

Advanced methods like AI and machine learning are uniquely poised to help scientists uncover the full spectrum of patient placebo responsiveness in a clinical trial. Learn more about this approach by attending our webinar, which explains how a solution like Placebell©™ leverages a time-tested predictive…

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