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Publication

Leveraging historical data for high-dimensional regression adjustment, a machine learning approach.

The amount of data collected from patients involved in clinical trials is continuously growing. All those patient’s characteristics…

Type: Scientific Presentation
Authors: Samuel Branders, PhD; Guillaume Bernard, PhD; Alvaro Pereira, PhD
Conference: Promoting Statistical Insight Conference
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Publication

Baseline Pain Measurements As Predictors Of The Placebo Response In Neuropathic Patients

In analgesia randomized clinical trials (RCTs), the magnitude of the placebo response has a negative influence when testing…

Type: Scientific Poster
Authors: Alvaro Pereira, PHD; Samuel Branders, PHD; Christian Dualé, MD PHD; Fréderic Clermont, PHD; Pierre Gramme, MS; Chantal Gossuin, PHARMD; Dominique Demolle, PHD
Conference: SIPS Conference
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Publication

Bayesian Modeling Of The Placebo Response In Neuropathic Pain

In analgesia randomized clinical trials (RCTs), the magnitude and the variability of the placebo response have a negative…

Type: Scientific Poster
Authors: Samuel Branders, PhD; Alvaro Pereira, PhD; Frederic Clermont, PhD; Chantal Gossuin; Dominique Demolle, PhD
Conference: Promoting Statistical Insight Conference
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Publication

Multifactorial Aspect Of The Placebo Analgesia Response In Peripheral Neuropathic Patients

The placebo response exerts a confusing influence when testing the statistically significant superiority of active compounds compared to…

Type: Scientific Poster
Authors: Alvaro Pereira, PHD; Samuel Branders, PHD; Christian Dualé, MD PHD; Fréderic Clermont, PHD; Pierre Gramme, MS; Chantal Gossuin, PHARMD; Dominique Demolle, PHD.
Conference: International Association for the Study of Pain Conference
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Publication

Characterization And Prediction Of Placebo Responders In Peripheral Neuropathic Patients In A 4-week Analgesic Clinical Trial

In analgesia randomized clinical trials (RCTs), the magnitude of the placebo response tends to increase with the year…

Type: Scientific Poster
Authors: Alvaro Pereira, PHD; Christian Dualé, MD PHD; Frédéric Clermont, PHD, Pierre Gramme, MS; Samuel Branders, PHD; Chantal Gossuin, PHARMD; Dominique Demolle, PHD
Conference: American Pain Society Conference
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Publication

Do Environmental Parameters Influence The Prediction Of The Placebo Response?

This proof-of-concept study on peripheral neuropathic pain patients investigates the potential influence of the investigator on the placebo…

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