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Embracing Human Complexity in Clinical Research
As clinical trials become more diverse, patient heterogeneity, placebo responses, and inter-site variability become more pronounced, contributing to high rates of failed trials and extended development timelines…
Clinical Trial Technology: Why IT Infrastructure & Security Matters
From internal communication and management systems to tools sponsors deploy to improve operations and results, technology is everywhere in the clinical trial landscape. However, these technologies are…
Clinical Trial Technology & Project Management:
4 Aspects of Cognivia’s Approach
Many sponsors err on the side of reluctance when incorporating new technology in clinical trials. This is because some technologies have the potential to overly burden not…
Q&A: Experts’ Perspectives on the Placebo Response in Clinical Trials
Experts shared their perspectives from real-world trials on both classical and new approaches to manage the placebo response – and some questions arose throughout the discussion.
The Power of Placebo & Trust for Pain Management
A growing body of work has demonstrated that pain perception can be modulated by social, cultural, contextual and interpersonal factors.1,2,3,4 Beyond this, patient trust in their doctor –…
Q&A: Developing a Custom e-Questionnaire Data Management Solution for Clinical Trials
Q&A Interview with Gilles Scuttenaire, Senior Software Engineer In a presentation at BIO IT World 2022, Cognivia’s Gilles Scuttenaire, senior Software Engineer, discussed our custom, end-to-end data management…
The placebo problem in pain: does baseline pain variability predict placebo response?
Recent reports have demonstrated a positive correlation between baseline pain variability and improvement in clinical trial patients receiving placebo, suggesting that patients with more highly variable reporting…
Understand patient differences in your next clinical trial
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